Orin is a Reader in Infectious Disease Epidemiology at the University of Warwick and member of the Warwick Infectious Disease & Epidemiology Research group (WIDER).
His interests are in applied epidemiology necessitating cross-disciplinary skills in medical entomology, behavioural ecology, and molecular diagnostics, in addition to quantitative analysis. He has conducted field research on the diagnostics, epidemiology and control of visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) in many endemic regions. His work addresses basic biology to policy driven questions. These include identification of domestic and sylvatic transmission cycles and the relative role of hosts in transmission, modeling MoH VL control strategies, in addition to entomological cross-over and community studies to evaluate potential use of ITNs and topical insecticide formulations to reduce vector biting rates. He is/has been supported by industrial partners to conduct Phase I-III efficacy trials to test Leishmania vaccine candidates against infection and transmission and topical insecticides. Policy driven work includes improving diagnostic strategies to detect “super-spreaders” (i.e. individuals disproportionately contributing to transmission), towards more cost-effective VL management.
More recently, he acts as Special Visiting Scientist to the Brazilian MoH, Fundação Oswaldo Cruz (2012-2016) to coordinate science and to train local PG students. He is part of a B&M Gates consortium initiative based at Warwick to model leishmaniasis in line with the London Declaration on reducing the burden of Neglected Tropical Diseases.